The use of high-dose omega-3 fatty acids in the management of cardiovascular disease
Keywords:Omega-3 fatty acids Cardiovascular diseases Resolvins Omega-3 index, AA / EPA ratio
AbstractHigh-dose omega-3 fatty acids rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can have significant benefits in the management of cardiovascular disease due to their formation of specialized hormones known as resolvins. The appropriate dose can be determined by the ratio of arachidonic acid (AA) to EPA in the blood. This review will summarize the recent data on reducing the AA/EPA ratio and its effects on cardiovascular outcomes.