Clinical evaluation of a hyaluronic acid-based medical device in counteracting aphthous stomatitis in adults
Keywords:Mucositis, oral ulcers, chlorhexidine, Aloe barbadensis, Rosa damascena
AbstractOral mucosal ulcers are quite common in an otherwise healthy population, and can determine a real worsening of the quality of life. Conventional therapy is not appropriate since ulcers often recur and, even if not needed, therapy lasting not less than 2–3 weeks carries a high risk of serious side effects. The use of hyaluronic acid applied as an adhesive gel over the lesions seems to have potential in terms of efficacy and the avoidance of side effects. Of course, hyaluronic acid-based formulations show different effects and tolerability. In our study, we retrospectively report the results obtained using a medical device, Bloxaphte®, applied for 14 days to counteract ulcers in adults. Our data clearly demonstrate the healing capability and safety profile of the product in reducing the number and size of the ulcers within the first week of daily application.