Hair loss in older women: supplement to increase scalp hair thickness and reduce hair loss
Hair loss and thinning hair are serious problems affecting a large number of women, especially during the menopause. A food supplement containing fermented soy, ornithine, arginine and Tricovel® Tricoage45+ with Bioequolo (Giuliani SpA, Milan, Italy), formulated to promote hair growth in women over the age of 45, was used in a double-blind, placebo-controlled study conducted in healthy adult females going through the menopause. Subjects with hair loss and less than 80% of their hair in the anagen phase were randomized to receive a single daily dose of the study product or placebo. Wash test results showed that hair loss was significantly reduced after the first 8 weeks of treatment with the study product. Hair pull test results also showed significant improvements (fewer hairs removed) in subjects treated with the study product vs. placebo after 8 and 12 weeks of treatment. Moreover, analysis of microscope images revealed a statistically significant increase in the conversion of vellus hair into terminal hair after 12 weeks of treatment with the study product compared with placebo. Self-evaluation by the subjects confirmed these improvements. This study shows that the dietary supplement can decrease hair loss and promote hair growth in women over 45 years of age.
DOI: 10.17470/NF-017-1012-4
DATE: 2017
AUTHOR/S: Mastropietro F, Corasaniti N, Piacentini M, Celleno L
ABSTRACT:
Hair loss and thinning hair are serious problems affecting a large number of women, especially during the menopause. A food supplement containing fermented soy, ornithine, arginine and Tricovel® Tricoage45+ with Bioequolo (Giuliani SpA, Milan, Italy), formulated to promote hair growth in women over the age of 45, was used in a double-blind, placebo-controlled study conducted in healthy adult females going through the menopause. Subjects with hair loss and less than 80% of their hair in the anagen phase were randomized to receive a single daily dose of the study product or placebo. Wash test results showed that hair loss was significantly reduced after the first 8 weeks of treatment with the study product. Hair pull test results also showed significant improvements (fewer hairs removed) in subjects treated with the study product vs. placebo after 8 and 12 weeks of treatment. Moreover, analysis of microscope images revealed a statistically significant increase in the conversion of vellus hair into terminal hair after 12 weeks of treatment with the study product compared with placebo. Self-evaluation by the subjects confirmed these improvements. This study shows that the dietary supplement can decrease hair loss and promote hair growth in women over 45 years of age.
KEYWORDS:
Clinical trial, Anti-hair loss supplement, Women, Menopause
10.17470/NF-017-1012-4